{"query":"creatine strength","matched_outcome":{"id":"muscle-strength","name":"Muscle Strength"},"ingredients":[{"type":"supplement","id":"creatine","name":"Creatine","category":"amino_acid","evidence_quality":"strong","study_count":555,"reason":"name match + Muscle Strength"},{"type":"supplement","id":"protein","name":"Protein","category":"amino_acid","evidence_quality":"strong","study_count":1610,"reason":"established for Muscle Strength"},{"type":"supplement","id":"caffeine","name":"Caffeine","category":"other","evidence_quality":"strong","study_count":821,"reason":"established for Muscle Strength"},{"type":"supplement","id":"citrulline","name":"Citrulline","category":"amino_acid","evidence_quality":"strong","study_count":189,"reason":"probable for Muscle Strength"},{"type":"supplement","id":"whey-protein","name":"Whey Protein","category":"amino_acid","evidence_quality":"strong","study_count":443,"reason":"probable for Muscle Strength"}],"studies":[{"type":"study","pmid":"28251287","title":"Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review.","year":2017,"study_type":"systematic-review","direction":"mixed","takeaway":"Exercise is the primary driver of muscle health in seniors; nutritional supplements offer limited additional benefit for those who are already well-n…"},{"type":"study","pmid":"22513923","title":"Treatment for mitochondrial disorders.","year":2012,"study_type":"meta-analysis","direction":"mixed","takeaway":"There is no clear evidence that common supplements like CoQ10 or creatine provide consistent clinical benefits for mitochondrial disease patients, th…"},{"type":"study","pmid":"9390981","title":"Long-term creatine intake is beneficial to muscle performance during resistance training.","year":1997,"study_type":"rct","direction":"positive","takeaway":"Long-term creatine supplementation combined with resistance training significantly accelerates strength and lean mass gains in women, even during per…"},{"type":"study","pmid":"9475647","title":"Effects of creatine supplementation on body composition, strength, and sprint performance.","year":1998,"study_type":"rct","direction":"positive","takeaway":"Creatine supplementation significantly enhances lean mass gains, lifting volume, and initial sprint performance in elite athletes undergoing intensiv…"},{"type":"study","pmid":"8941534","title":"Effect of leucine metabolite beta-hydroxy-beta-methylbutyrate on muscle metabolism during resistance-exercise training.","year":1996,"study_type":"rct","direction":"positive","takeaway":"HMB supplementation can reduce muscle damage and enhance lean mass and strength gains in individuals starting a new resistance training program."}],"exercises":[]}